The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Jun. 21, 2017
Acroimmune Biotech Co., Ltd., Guangzhou, CN;
Hongqun Hu, Suzhou, CN;
Zui Chen, Suzhou, CN;
Xiaoqi Song, Suzhou, CN;
Shiping Luo, Suzhou, CN;
Mingwen Cai, Suzhou, CN;
Jinling Fan, Suzhou, CN;
Yiqing Xu, Suzhou, CN;
Qunmin Zhou, Suzhou, CN;
AcroImmune Biopharma Co., Ltd., Nanjing, CN;
Abstract
A monoclonal antibody or a derivative thereof which can antagonize and inhibit the binding of human PD-1 antigen to its ligand: the amino acid sequences of CDR1, CDR 2 and CDR 3 in the light chain variable region of the antibody are shown in SEQ ID NO:3, SEQ ID NO: 4 and SEQ ID NO: 5, respectively, while the amino acid sequences of CDR 1, CDR 2 and CDR 3 in the heavy chain variable region are shown in SEQ ID NO: 8, SEQ ID NO: 9 and SEQ ID NO: 10, respectively. A humanization preparation process for the antibody and the amino acid sequences of the heavy chain variable region and light chain variable region of the humanized antibody.