The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Jul. 31, 2017
Momenta Pharmaceuticals, Inc., Cambridge, MA (US);
Leona E. Ling, Winchester, MA (US);
Sucharita Roy, Acton, MA (US);
Nathaniel Washburn, Cambridge, MA (US);
Marilyn Kehry, San Diego, CA (US);
David J. King, Encinitas, CA (US);
Anthony Manning, Cambridge, MA (US);
James Meador, III, Framingham, MA (US);
Jan Hillson, Cambridge, MA (US);
MOMENTA PHARMACEUTICALS, INC., Cambridge, MA (US);
Abstract
The present application features antibodies that bind to human neonatal Fc receptor (FcRn). These anti-FcRn antibodies are useful, e.g., to promote clearance of autoantibodies in a subject, to suppress antigen presentation in a subject, to block an immune response, e.g., block an immune complex-based activation of the immune response in a subject, and to treat immunological diseases (e.g., autoimmune diseases) in a subject. These anti-FcRn antibodies are also useful, e.g., to decrease pathogenic antibody transport across the placenta of a pregnant subject, to increase pathogenic antibody catabolism in a pregnant subject, and to treat an antibody-mediated enhancement of viral disease in a fetus or a neonate.