The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Dec. 15, 2021
Applicants:

The Queen's University of Belfast, Belfast, GB;

Chromadex Inc., Irvine, CA (US);

Inventors:

Marie Eugenie Migaud, Lurgan, GB;

Philip Redpath, Portadown, GB;

Kerri Crossey, Magherafelt, GB;

Richard Cunningham, Portadown, GB;

Aron Erickson, Longmont, CO (US);

Richard Nygaard, Longmont, CO (US);

Amanda Storjohann, Westminster, CO (US);

Assignees:

The Queen's University of Belfast, Belfast, GB;

ChromaDex Inc., Irvine, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/207 (2006.01); C07H 19/048 (2006.01); C07D 307/20 (2006.01); C07H 19/20 (2006.01); C07H 19/04 (2006.01);
U.S. Cl.
CPC ...
C07H 19/048 (2013.01); C07D 307/20 (2013.01); C07H 19/20 (2013.01); C07B 2200/13 (2013.01); C07H 19/04 (2013.01);
Abstract

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X, Z, Z, n, R, R, R, R, R, R, R, and Rare described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof; and novel crystalline forms thereof.


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