The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Sep. 16, 2020
Applicant:

Shionogi & Co., Ltd., Osaka, JP;

Inventors:

Hiroyuki Tobinaga, Osaka, JP;

Koji Masuda, Osaka, JP;

Satoshi Kasuya, Osaka, JP;

Masanao Inagaki, Osaka, JP;

Manami Masuda, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 31/4985 (2006.01); A61K 31/519 (2006.01); A61K 31/55 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 25/30 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); C07D 513/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); A61K 31/437 (2006.01); C07D 513/08 (2006.01); A61K 31/5377 (2006.01); A61P 39/02 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/437 (2013.01); A61K 31/4709 (2013.01); A61K 31/4985 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61P 25/18 (2018.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01); A61P 25/30 (2018.01); A61P 39/02 (2018.01); A61P 43/00 (2018.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 513/08 (2013.01); C07D 519/00 (2013.01); Y02P 20/55 (2015.11);
Abstract

Novel compounds having D3 receptor antagonistic activity are provided. A compound represented by formula (I): whereinring A is a heterocycle, Xis each independently CRR, Xis each independently CRR, Yand Yare each independently a carbon atom or a nitrogen atom,L is —N(R)—C(═O)— or the like, W is cyclyl or the like, Rand Rare each independently substituted or unsubstituted alkyl or the like, R, R, Rto R, and Rare each independently hydrogen atoms or the like,p is 1 or 2, q is an integer of 1 to 3, n is an integer of 1 to 4, s is an integer of 0 to 4, or a pharmaceutically acceptable salt thereof.


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