The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Jan. 23, 2019
Applicant:
Shenzhen Targetrx, Inc., Guangdong, CN;
Inventors:
Yihan Wang, Guangdong, CN;
Jiuyang Zhao, Guangdong, CN;
Assignee:
SHENZHEN TARGETRX, INC., Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/22 (2006.01);
U.S. Cl.
CPC ...
C07D 471/22 (2013.01);
Abstract
Provided are a pharmaceutical composition of a substituted pyrazolo[1,5-a]pyrimidine macrocyclic compound and the use thereof. The pyrazolo[1,5-a]pyrimidine macrocyclic compound is a compound as shown in formula (Aa), or a pharmaceutically acceptable salt, a prodrug, a hydrate or a solvate, a crystal form, a stereoisomer or an isotopic variant thereof. The compound of the present invention is an inhibitor of the Trk kinase, and can be used for treating pain, cancers, inflammation, neurodegenerative diseases and certain infectious diseases.