The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Feb. 09, 2017
Applicant:

Fresenius Medical Care Deutschland Gmbh, Bad Homburg, DE;

Inventors:

Andreas Laubrock, Wehrheim, DE;

Rainer Fislage, St. Wendel, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2006.01); A61M 1/34 (2006.01); C12N 11/12 (2006.01);
U.S. Cl.
CPC ...
A61M 1/3687 (2013.01); A61M 1/34 (2013.01); A61M 1/3482 (2014.02); A61M 1/3486 (2014.02); A61M 1/3489 (2014.02); A61M 1/36 (2013.01); A61M 1/3689 (2014.02); C12N 11/12 (2013.01); A61M 2202/0415 (2013.01); A61M 2202/20 (2013.01); A61M 2202/203 (2013.01); A61M 2202/206 (2013.01);
Abstract

The present invention relates to a device for the treatment of blood comprising a solid phase on which a polypeptide is immobilized which is suitable for the inactivation of free nucleic acids. Suitable polypeptides are, for example, deoxyribonucleases, ribonucleases, DNA methyltransferases or cytosine deaminases. The invention further comprises the use of such devices for the treatment of patients suffering from chronic kidney failure, cancer or lupus erythematosus, as well as methods and systems for the treatment of blood, wherein free nucleic acids are inactivated outside the body.


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