The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Jul. 19, 2018
Applicants:

Auckland Uniservices Limited, Auckland, NZ;

Ocunexus Therapeutics, Inc., San Diego, CA (US);

Inventors:

Colin Richard Green, Auckland, NZ;

Odunayo Omolola Boluwarin Mugisho, Auckland, NZ;

Bradford James Duft, Rancho Santa Fe, CA (US);

Assignees:

AUCKLAND UNISERVICES LIMITED, Auckland, NZ;

OCUNEXUS THERAPEUTICS, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/10 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01);
Abstract

The inventions relate to the use of hemichannel blockers to modulate cytokine levels in a subject, including the angiogenic cytokine, VEGF, and their production, secretion and/or release, and to the use of hemichannel blockers to reduce or level cytokine activity, including in conditions characterized in whole or in part by angiogenesis and/or vessel leak.


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