The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Jan. 26, 2017
Applicant:
Oxford University Innovation Limited, Oxford, GB;
Inventor:
Paul J. Fairchild, Oxford, GB;
Assignee:
OXFORD UNIVERSITY INNOVATION LIMITED, Oxfordshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); C12N 5/0784 (2010.01); C12N 5/074 (2010.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); C12N 5/0786 (2010.01); C12N 15/86 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61P 31/00 (2018.01); A61P 35/00 (2018.01); C12N 5/0639 (2013.01); C12N 5/0645 (2013.01); C12N 5/0696 (2013.01); C12N 15/86 (2013.01); G01N 33/505 (2013.01); C12N 2501/22 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/65 (2013.01); C12N 2501/999 (2013.01); C12N 2506/11 (2013.01); C12N 2740/15011 (2013.01);
Abstract
The invention relates to induced pluripotent stem cells (iPSCs) produced from source dendritic cells (DCs). The invention also relates to synthetic DCs re-differentiated the iPSCs and which display a definitive adult phenotype rather than a primitive fetal/neonatal phenotype. The invention also relates to methods for making and methods of using the iPSCs and DCs of the invention.