The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Sep. 26, 2018
Applicant:
Duke University, Durham, NC (US);
Inventors:
Ines Batinic-Haberle, Durham, NC (US);
Artak Tovmasyan, Durham, NC (US);
Ivan Spasojevic, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 13/00 (2006.01); A61K 33/32 (2006.01); A61P 39/00 (2006.01); A61P 35/00 (2006.01); A61K 31/375 (2006.01);
U.S. Cl.
CPC ...
A61K 33/32 (2013.01); A61K 31/375 (2013.01); A61P 35/00 (2018.01); A61P 39/00 (2018.01); C07F 13/005 (2013.01);
Abstract
Provided herein are fluoro-substituted porphyrin compounds, such as those having a structure represented by Formula (I), wherein Ris a C1-C8 alkyl that is substituted with at least 1 fluorine (e.g., a C1-C8 alkyl substituted with 1-17 fluorine atoms); and X is an anion (e.g. a halogen ion (e.g., chloride, etc.), PF, tosylate, besylate, and/or mesylate). Also provided herein are methods of making the fluoro-substituted porphyrin compounds, pharmaceutical formulations containing the same, and methods of use thereof.