The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Oct. 23, 2018
Applicant:
Procos S.p.a., Cameri, IT;
Inventors:
Fabio Morana, Novara, IT;
Stefano Gobbato, Cameri, IT;
Lucia Cozzi, Brescia, IT;
Jacopo Roletto, Turin, IT;
Paolo Paissoni, Druento, IT;
Assignee:
Procos S.P.A., Cameri, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); A61K 31/513 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); C07B 2200/13 (2013.01); C07D 403/06 (2013.01);
Abstract
The present invention concerns a process for the preparation of the crystalline form III of Tipiracil hydrochloride having a content of residual solvents lower than the ICH limits. Said process is advantageous with respect to the known processes because it allows the production of the form III of Tipiracil hydrochloride suitable for use in the preparation of pharmaceutical finished products.