The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Sep. 05, 2014
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Michael J. Cima, Winchester, MA (US);

Matthew Li, Somerville, MA (US);

Christophoros C. Vassiliou, El Cerrito, CA (US);

Negar Tavassolian, Hoboken, NJ (US);

Lina Avancini Colucci, Lexington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); G01R 33/50 (2006.01); G01R 33/383 (2006.01); A61B 5/00 (2006.01); A61B 5/02 (2006.01); G01R 33/44 (2006.01); G01R 33/46 (2006.01); A61B 5/145 (2006.01);
U.S. Cl.
CPC ...
A61B 5/055 (2013.01); A61B 5/02 (2013.01); A61B 5/443 (2013.01); A61B 5/4875 (2013.01); A61B 5/6826 (2013.01); G01R 33/383 (2013.01); G01R 33/448 (2013.01); G01R 33/4608 (2013.01); G01R 33/50 (2013.01); A61B 5/14535 (2013.01); A61B 5/14542 (2013.01); A61B 2560/0431 (2013.01);
Abstract

The invention features methods for detecting the hydration state or vascular volume of a subject using a device capable of nuclear magnetic resonance (NMR) measurement. The methods involve exposing a portion of a tissue of the subject in vivo to a magnetic field and RF pulse from the device to excite hydrogen nuclei of water within the tissue portion, and measuring a relaxation parameter of the hydrogen nuclei in the tissue portion, the relaxation parameter being a quantitative measure of the hydration state or vascular volume of the subject as a whole. The invention also features devices and computer-readable storage media for performing the methods of the invention.


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