The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Apr. 28, 2016
Applicant:
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, CN;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); C12Q 1/6851 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/686 (2018.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01); C12N 5/077 (2010.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); C12N 5/0658 (2013.01); C12Q 1/025 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6851 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5061 (2013.01); G01N 33/68 (2013.01); G01N 33/6854 (2013.01); G01N 33/6887 (2013.01); C12N 2503/02 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Disclosed are a protein molecular marker Dkk-3 protein associated with age-related muscle atrophy and the use thereof in the diagnosis of age-related muscle atrophy. The expression level of the Dkk-3 protein in amyotrophic cells is significantly higher than that in normal myocytes or tissues, and thus the Dkk-3 protein can be used as an effective marker for the detection of age-related muscle atrophy.