The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Mar. 09, 2017
Applicant:
The Government of the United States of America, As Represented BY the Secretary of the Navy, Arlington, VA (US);
Inventor:
David A. Kidwell, Alexandria, VA (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/558 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 11/02 (2006.01); G01N 33/532 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5306 (2013.01); G01N 11/02 (2013.01); G01N 33/532 (2013.01); G01N 33/54306 (2013.01); G01N 33/54333 (2013.01); G01N 33/54346 (2013.01); G01N 33/54353 (2013.01); G01N 33/54387 (2021.08); G01N 33/54388 (2021.08); G01N 33/54393 (2013.01); G01N 33/558 (2013.01);
Abstract
The present invention provides a method for preparing colloidal palladium nanoparticles and using them for increased sensitivity in lateral flow immunoassays. Glutaraldehyde is used in preparing the colloidal palladium that allows rapid attachment of biomolecules. Colloidal palladium nanoparticles are labeled with a protein, such as a biomolecule or an antibody. These labeled colloidal palladium particles catalytically develop a dye to detect the presence of an analyte.