The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Oct. 16, 2019
Applicant:

Factor Bioscience Inc., Cambridge, MA (US);

Inventors:

Matthew Angel, Cambridge, MA (US);

Christopher Rohde, Cambridge, MA (US);

Assignee:

FACTOR BIOSCIENCE INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/63 (2006.01); C12N 15/90 (2006.01); A61K 31/7115 (2006.01); C12N 9/22 (2006.01); C07K 14/195 (2006.01); C12N 15/10 (2006.01); A61K 35/14 (2015.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); C12N 15/86 (2006.01); G01N 33/50 (2006.01); A61K 31/70 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); A61K 31/7115 (2013.01); A61K 35/14 (2013.01); A61K 38/465 (2013.01); A61K 48/005 (2013.01); C07K 14/195 (2013.01); C12N 9/22 (2013.01); C12N 15/1024 (2013.01); C12N 15/86 (2013.01); C12Y 301/00 (2013.01); C12Y 301/21004 (2013.01); G01N 33/5014 (2013.01); A61K 2035/124 (2013.01); C07K 2319/80 (2013.01); C12N 2800/80 (2013.01);
Abstract

The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.


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