The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Sep. 09, 2016
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Feng Zhang, Cambridge, MA (US);
Joshua Asher Weinstein, Cambridge, MA (US);
Aviv Regev, Cambridge, MA (US);
Assignees:
THE BROAD INSTITUTE, INC., Cambridge, MA (US);
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6841 (2018.01); C12Q 1/686 (2018.01); C12N 15/10 (2006.01); C40B 40/08 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C12N 15/1096 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6841 (2013.01); C40B 40/08 (2013.01); G01N 33/5082 (2013.01); C12Q 2535/122 (2013.01); C12Q 2537/165 (2013.01); C12Q 2543/101 (2013.01); C12Q 2563/179 (2013.01); C12Q 2565/514 (2013.01); G01N 33/5023 (2013.01);
Abstract
The present invention relates to DNA microscopy methods to record the cellular co-localization and/or spatial distributions of arbitrary nucleic acid sequences, or other biomolecules tagged with nucleic sequences. The method involves sequence-components which may identify the targeted sequences-of-interest themselves and/or spatial beacons relative to which their distances are measured.