The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

May. 03, 2017
Applicants:

Cheng LI, Beijing, CN;

Lei Guo, Beijing, CN;

Sclnow Biotechnology Co., Ltd, Beijing, CN;

Inventor:

Lei Guo, Beijing, CN;

Assignees:

Other;

SCLNOW BIOTECHNOLOGY CO., LTD., Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0668 (2013.01); C12N 5/0665 (2013.01); C12N 5/0676 (2013.01); C12N 2500/25 (2013.01); C12N 2500/30 (2013.01); C12N 2500/32 (2013.01); C12N 2500/34 (2013.01); C12N 2500/90 (2013.01); C12N 2500/99 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/12 (2013.01); C12N 2501/345 (2013.01); C12N 2506/1369 (2013.01); C12N 2506/1392 (2013.01);
Abstract

Provided is a new type serum-free medium. The medium comprises: DMEM with high glucose (the content of glucose being 4.5 g/L), B27, recombinant human basic fibrolast growth factor (b-FGF), nicotinamide, N-2, vinblastine III (conophylline), non-essential amino acid (NEAA), heparin, epidermal growth factor (EGF), hepatocyte growth factor (HGF), a serum replacement (SR), an insulin-transferrin-selenium complex (ITS), and pentagastrin. Inducing differentiation of mesenchymal stem cells into insulin-secretion-like cells can be achieved in six days in one step using the medium.


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Guo, Lei. (2022). Serum-free medium inducing differentiation of umbilical cord mesenchymal stem cell into insulin-secretion-like cell and preparation method and use thereof (U.S. Patent No. 11339372). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11339372

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