The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Mar. 29, 2019
Applicants:

Kezar Life Sciences, South San Francisco, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Dustin McMinn, Pacifica, CA (US);

John William Taunton, San Francisco, CA (US);

Phillip Patrick Sharp, San Francisco, CA (US);

Assignees:

KEZAR LIFE SCIENCES, South San Francisco, CA (US);

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 11/00 (2006.01); C07K 11/02 (2006.01); A61K 38/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 11/02 (2013.01); A61K 38/00 (2013.01); A61K 45/06 (2013.01);
Abstract

Provided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation.


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