The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Jul. 20, 2017
Applicant:
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Matthew R. Redinbo, Chapel Hill, NC (US);
Jian Jin, New York, NY (US);
Lindsey James, Chapel Hill, NC (US);
Sam Pellock, Chapel Hill, NC (US);
Ranathunga Arachchillage Yamuna Ariyarathna, Carrboro, NC (US);
Stephen Frye, Chapel Hill, NC (US);
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 251/00 (2006.01); C07D 253/00 (2006.01); C07D 495/00 (2006.01); C07D 513/14 (2006.01);
U.S. Cl.
CPC ...
C07D 513/14 (2013.01);
Abstract
Compounds and compositions are provided that comprise selective b-glucuronidase inhibitors. The compounds and compositions can ameliorate the side effects of chemotherapeutic agents and can improve the efficacy of such agents, including irinotecan and non-steroidal anti-inflammatory drugs.