The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

May. 18, 2020
Applicants:

Ottawa Hospital Research Institute, Ottawa, CA;

University of Ottawa, Ottawa, CA;

Inventors:

Jean-Simon Diallo, Ottawa, CA;

Christopher Noyce Boddy, Ottawa, CA;

Mark Dornan, Ottawa, CA;

Ramya Krishnan, Ottawa, CA;

Rozanne Arulanandam, Ottawa, CA;

Fabrice Le Boeuf, Gatineau, CA;

Jeffrey Smith, Ottawa, CA;

Andrew Macklin, Ottawa, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); C07D 413/06 (2006.01); C07D 237/14 (2006.01); C07D 207/38 (2006.01); C07D 307/60 (2006.01); C07D 307/66 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 409/06 (2006.01); C07D 307/30 (2006.01); C07D 307/58 (2006.01); C07D 405/06 (2006.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01); C07D 207/36 (2006.01); C07D 207/456 (2006.01); C07D 317/64 (2006.01); C07D 417/06 (2006.01); C07D 471/04 (2006.01); A61P 35/02 (2006.01); C07D 209/48 (2006.01); C07D 231/08 (2006.01); A61K 31/341 (2006.01);
U.S. Cl.
CPC ...
C07D 413/06 (2013.01); A61K 31/501 (2013.01); A61K 45/06 (2013.01); A61P 35/02 (2018.01); C07D 207/36 (2013.01); C07D 207/38 (2013.01); C07D 207/456 (2013.01); C07D 209/48 (2013.01); C07D 231/08 (2013.01); C07D 237/14 (2013.01); C07D 307/30 (2013.01); C07D 307/58 (2013.01); C07D 307/60 (2013.01); C07D 307/66 (2013.01); C07D 317/64 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 409/06 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); C12N 7/00 (2013.01); A61K 31/341 (2013.01); A61K 2300/00 (2013.01); C12N 2710/10334 (2013.01); C12N 2710/10351 (2013.01); C12N 2710/10352 (2013.01); C12N 2710/16651 (2013.01); C12N 2710/24151 (2013.01); C12N 2750/14151 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/16152 (2013.01); C12N 2760/20234 (2013.01); C12N 2760/20251 (2013.01); C12N 2760/20252 (2013.01);
Abstract

Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.


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