The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Sep. 06, 2018
Applicant:

Recurium Ip Holdings, Llc, San Diego, CA (US);

Inventors:

Joseph Robert Pinchman, San Diego, CA (US);

Kevin Duane Bunker, Escondido, CA (US);

Matthew M. Bio, Cambridge, MA (US);

Christopher Breen, Cambridge, MA (US);

Andrew M. Clausen, Cambridge, MA (US);

Yuanqing Fang, Cambridge, MA (US);

Hui Li, Cambridge, MA (US);

Jillian W. Sheeran, Cambridge, MA (US);

Assignee:

RECURIUM IP HOLDINGS, LLC, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 1/28 (2006.01); B01J 31/12 (2006.01); B01J 19/12 (2006.01); B01J 19/00 (2006.01); B01J 23/44 (2006.01); B01J 23/755 (2006.01); C07C 7/144 (2006.01); C07C 209/02 (2006.01); C07C 13/605 (2006.01); C07C 211/38 (2006.01);
U.S. Cl.
CPC ...
C07C 1/28 (2013.01); B01J 19/002 (2013.01); B01J 19/0053 (2013.01); B01J 19/123 (2013.01); B01J 23/44 (2013.01); B01J 23/755 (2013.01); C07C 7/144 (2013.01); C07C 209/02 (2013.01); B01J 2219/00033 (2013.01); B01J 2219/00051 (2013.01); B01J 2219/00166 (2013.01); C07C 13/605 (2013.01); C07C 211/38 (2013.01); C07C 2523/04 (2013.01); C07C 2523/06 (2013.01); C07C 2527/24 (2013.01); C07C 2602/38 (2017.05); C07C 2603/62 (2017.05);
Abstract

Processes for making bicyclic compounds and precursors thereof, and particularly for making [1.1.1]propellane and bicyclo[1.1.1]pentane and derivatives thereof, utilize continuous flow reaction methods and conditions. A continuous process for making [1.1.1]propellane can be conducted under reaction conditions that advantageously minimize clogging of a continuous flow reactor. A continuous flow process can be used to make precursors of [1.1.1]propellane.


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