The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Dec. 26, 2017
Applicants:

Imec Vzw, Leuven, BE;

Katholieke Universiteit Leuven, Ku Leuven R&d, Leuven, BE;

Inventors:

Koen Johannes Hubertus Gerardus de Wijs, Kessel-Lo, BE;

Chengxun Liu, Kessel-Lo, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/00 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 7/54 (2013.01); G01N 15/10 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/147 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/0442 (2013.01); G01N 2015/1081 (2013.01);
Abstract

Disclosed herein are microfluidic actuators for selecting objects in a fluid stream comprising a plurality of objects. In some embodiments, the actuator comprises an object detection means adapted for, upon arrival of an object, identifying whether an object is an object of interest. It further comprises a heater adapted for generating a jet flow for deflecting an object of interest from the fluid stream and a controller for activating the heater as function of the detection of an object of interest using a nucleation signal. The controller is adapted for obtaining temperature information of the heater and for adjusting a nucleation signal for the heater taking into account the obtained temperature information. Also disclosed are microfluidic systems and diagnostic devices comprising the microfluidic actuators of the disclosure, as well as methods of use thereof.


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