The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Mar. 15, 2017
Applicant:
Yamaguchi University, Yamaguchi, JP;
Inventors:
Assignee:
Yamaguchi University, Yamaguchi, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); A61K 39/00 (2006.01); C07K 14/54 (2006.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01); C12N 15/79 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 39/0011 (2013.01); C07K 14/5418 (2013.01); C07K 14/7051 (2013.01); C12N 5/0636 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); C12N 15/79 (2013.01);
Abstract
It is to provide an immunocompetent cell that expresses regulatory factors of immunocompetent cell immune function and possesses all of proliferative potential, viability, and the ability to accumulate a T cell, and an expression vector of regulatory factors of immune function for generating the immunocompetent cell. An immunocompetent cell expressing a cell surface molecule specifically recognizing a cancer antigen, interleukin 7 (IL-7), and CCL19 is generated. Preferably, the cell surface molecule specifically recognizing a cancer antigen is T cell receptor specifically recognizing the cancer antigen, and the immunocompetent cell is a T cell.