The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Oct. 31, 2018
Applicants:

Bayer Aktiengesellschaft, Leverkusen, DE;

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Nicole Biber, Wuppertal, DE;

Damian Brockschnieder, Haan, DE;

Florian Kölling, Wuppertal, DE;

Jörg Meding, Wuppertal, DE;

Hideki Miyatake Ondozabal, Berlin, DE;

Thomas Neubauer, Wuppertal, DE;

Martina Schäfer, Berlin, DE;

Dmitry Zubov, Remscheid, DE;

Carsten Terjung, Bochum, DE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 487/04 (2006.01); A61P 11/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 45/06 (2013.01); A61P 11/00 (2018.01); C07D 487/04 (2013.01);
Abstract

The invention relates to prolyl endopeptidase (PREP) inhibitors of formula (I) which contain a condensed 2,4-dihydro-3H-1,2,4-triazol-3-one ring system, methods for producing same, the use thereof alone or in combinations for treating and/or preventing diseases, and the use thereof for producing drugs for treating and/or preventing diseases, in particular for treating and/or preventing inflammatory lung diseases (COPD).


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