The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Jul. 06, 2017
Applicants:
University of South Florida, Tampa, FL (US);
University of Florida Research Foundation, Inc., Gainesville, FL (US);
Inventors:
Mildred Acevedo-Duncan, Plant City, FL (US);
Anisul Islam, Tampa, FL (US);
David A. Ostrov, Gainesville, FL (US);
Assignees:
UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., Gainesville, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/185 (2006.01); C12Q 1/6886 (2018.01); G01N 33/50 (2006.01); A61K 31/675 (2006.01); A61K 31/122 (2006.01); C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/185 (2013.01); A61K 31/122 (2013.01); A61K 31/675 (2013.01); C12Q 1/485 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/91215 (2013.01); G01N 2800/52 (2013.01);
Abstract
The subject invention pertains to methods of treating colorectal cancer by administering an atypical PKC inhibitor. The inhibitors of aPKC useful in the methods of the instant invention include ACPD, ICA-1, DNDA and ζ-Stat. Also provided are methods of measuring the susceptibility of colon cancer cells of a subject to inhibitors of aPKCs.