The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Nov. 29, 2018
Applicant:

Max-delbrück-centrum Für Molekulare Medizin IN Der Helmholtz-gemeinschaft, Berlin, DE;

Inventors:

Michael Bader, Berlin, DE;

Fatimunnisa Qadri, Berlin, DE;

Mihail Todiras, Berlin, DE;

Natalia Alenina, Berlin, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/49 (2006.01); A61K 8/41 (2006.01); A61Q 5/08 (2006.01); A61Q 5/10 (2006.01); A61Q 17/04 (2006.01); A61Q 19/02 (2006.01); A61Q 19/04 (2006.01); A61K 9/00 (2006.01); A61K 31/4174 (2006.01); A61K 45/06 (2006.01); A61K 8/64 (2006.01); A61Q 19/00 (2006.01); A61P 17/00 (2006.01); A61K 8/35 (2006.01); A61K 8/40 (2006.01); A61K 9/70 (2006.01); A61K 31/655 (2006.01); A61K 38/34 (2006.01); A61P 35/00 (2006.01); C12N 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 8/4946 (2013.01); A61K 8/411 (2013.01); A61Q 5/08 (2013.01); A61Q 5/10 (2013.01); A61Q 17/04 (2013.01); A61Q 19/02 (2013.01); A61Q 19/04 (2013.01);
Abstract

A cosmetic method for modulating pigmentation in a subject includes administering a modulator of angiotensin-converting enzyme 2 (ACE2 modulator) to the subject. The ACE2 modulator can be an inhibitor of angiotensin-converting enzyme 2 (ACE2 inhibitor), in which case, the ACE2 inhibitor can be administered to increase pigmentation in the subject. The ACE2 modulator can also be an activator of angiotensin-converting enzyme 2 (ACE2 activator), in which case the ACE2 activator can be administered to decrease pigmentation in the subject. The treatment of inflammatory skin disease can also be achieved by inhibition of angiotensin-converting enzyme 2.


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