The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Apr. 04, 2014
Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Ravinder Reddy, Gladwynne, PA (US);

Ravi Prakash Reddy Nanga, Philadelphia, PA (US);

Hari Hariharan, Mount Laurel, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/055 (2006.01); G01R 33/56 (2006.01); A61M 5/00 (2006.01); A61B 5/145 (2006.01); G01R 33/46 (2006.01); G01R 33/483 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4848 (2013.01); A61B 5/055 (2013.01); A61B 5/14546 (2013.01); A61B 5/4064 (2013.01); A61B 5/4839 (2013.01); A61B 5/4866 (2013.01); A61M 5/007 (2013.01); G01R 33/46 (2013.01); G01R 33/483 (2013.01); G01R 33/5601 (2013.01); G01R 33/5605 (2013.01); A61B 2560/0475 (2013.01); A61B 2576/00 (2013.01);
Abstract

A magnetic resonance pulse sequence technique may acquire a water reference spectrum and two water suppressed metabolite spectra and with frequency selective inversion pulse centered at either single frequency, at multiple frequencies, or in a single acquisition. Subtraction of the inverted from non-inverted water suppressed metabolite spectrum results in single or a combination of specific metabolite peak/peaks alone with a flat baseline for easier quantification.


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