The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2022

Filed:

Jun. 26, 2020
Applicant:

Exocobio Inc., Seoul, KR;

Inventors:

Kwang Il Kim, Goyang-si, KR;

Byong Seung Cho, Gunpo-si, KR;

Yong Weon Yi, Seoul, KR;

Assignee:

ExoCoBio Inc., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 1/02 (2006.01); A61K 8/34 (2006.01); A61K 8/44 (2006.01); A61K 8/60 (2006.01); A61K 8/64 (2006.01); A61K 8/67 (2006.01); A61K 8/73 (2006.01); A61K 9/19 (2006.01); A61K 47/26 (2006.01); A61K 8/72 (2006.01); A61K 9/00 (2006.01); A61Q 19/00 (2006.01);
U.S. Cl.
CPC ...
A01N 1/0221 (2013.01); A01N 1/0284 (2013.01); A61K 8/345 (2013.01); A61K 8/447 (2013.01); A61K 8/60 (2013.01); A61K 8/606 (2013.01); A61K 8/64 (2013.01); A61K 8/671 (2013.01); A61K 8/676 (2013.01); A61K 8/735 (2013.01); A61K 9/19 (2013.01); A61K 47/26 (2013.01); A61K 8/72 (2013.01); A61K 9/0019 (2013.01); A61K 2800/84 (2013.01); A61Q 19/00 (2013.01);
Abstract

A method of lyophilizing exosomes using a cryoprotectant comprising methionine, mannitol and trehalose is disclosed. The lyophilized exosome product shows a good appearance which maintains a porous sponge shape without forming ice crystals. In addition, the lyophilized exosome product can be applied to a pharmaceutical composition, a skin external preparation and a cosmetic composition. For example, the lyophilized exosome product can be used as a solution obtained by simply mixing it with a diluent.


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