The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Jul. 31, 2017
Hipra Scientific, S.l.u., Amer, ES;
Consejo Superior DE Investigaciones Cientificas (Csic), Madrid, ES;
Xavier Gibert Pérez, Blanes, ES;
Marta Sitjà Arnau, Girona, ES;
Maria Mar Fenech Martínez, Barcelona, ES;
Santiago Francisco Elena Fito, Valencia, ES;
Susana Martín García, Valencia, ES;
HIPRA SCIENTIFIC, S.L.U., Amer, ES;
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), Madrid, ES;
Abstract
The present invention relates to a method for preparing cDNA infectious clones based on the genome of an attenuated Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and uses thereof for preparing efficacious and safety-enhanced vaccines against PRRSV. The invention further comprises an infectious cDNA clone obtainable by such method. The invention further provides an attenuated modified PRRSV, and immunogenic compositions and vaccines comprising that attenuated PRRSV. The present invention further provides the attenuated PRRSV for use in the prophylaxis and/or the treatment of PRRSV infections, and the attenuated PRRSV for use as vaccine or medicament in the prophylaxis and/or the treatment of PRRSV infections.