The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Nov. 02, 2018
Dezhou University, Shandong, CN;
Qing He, Dezhou, CN;
Qiangcheng Zeng, Dezhou, CN;
Lianying Zhang, Dezhou, CN;
Zhongmin Dai, Dezhou, CN;
Haixia Zhou, Dezhou, CN;
Mingyou Wang, Dezhou, CN;
Jianzhou Meng, Dezhou, CN;
DEZHOU UNIVERSITY, Dezhou, CN;
Abstract
An endophytic fungus from gingko, that is,DZHQ1 having antitumor activity and antibacterial activity, is isolated from the ginkgo bark. The species of the strain is determined by the combination of colonial morphology and 18 sRNA sequencing, and then the anti-cervical cancer activity of a crude extract of the strain is detected by MTT. Finally, a secondary metabolite of the strain with an inhibition rate of more than 50% is isolated by semi-preparative HPLC, which promotes the further screening of individual compounds with anti-tumor activity. Moreover, the metabolite of the endophytic fungus from gingko shows a more pronounced inhibition in the detection of activity againstand/or, and has potential use in the preparation of new antibacterial products.