The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2022

Filed:

Feb. 10, 2017
Applicant:

Sterling Ip Limited, Marlow, GB;

Inventors:

Patrick Hextall, London, GB;

Kim Suzanne Midwood, Oxford, GB;

Eric Culbert, London, GB;

Assignee:

STERLING IP LIMITED, Marlow, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); A61P 19/02 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61P 19/02 (2018.01); C12N 15/63 (2013.01); A61K 39/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01);
Abstract

The present disclosure relates to antibodies and binding fragments to a Tenascin, in particular the FBG domain of a Tenascin, which are potentially less immunogenic than the parent antibody. The disclosure also relates to compositions comprising the antibody or binding fragment and use of any one of the same for diagnosis, prognosis and/or treatment of disorders such as those associated with chronic inflammation. The disclosure further provides methods of making the antibodies.


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