The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2022

Filed:

Jul. 15, 2021
Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Ester Fernandez-Salas, San Mateo, CA (US);

Joanne Wang, Irvine, CA (US);

Patton E. Garay, Long Beach, CA (US);

Lina Wong, Irvine, CA (US);

D. Dianne Hodges, Tustin, CA (US);

Kei Roger Aoki, Coto De Caza, CA (US);

Assignee:

Allergan, Inc., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); G01N 33/68 (2006.01); G01N 33/566 (2006.01); G01N 33/50 (2006.01); C12Q 1/37 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1282 (2013.01); C12Q 1/37 (2013.01); G01N 33/5014 (2013.01); G01N 33/566 (2013.01); G01N 33/56911 (2013.01); G01N 33/6854 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); G01N 2333/33 (2013.01); G01N 2333/705 (2013.01); G01N 2333/952 (2013.01);
Abstract

The present specification discloses SNAP-25 compositions, methods of making α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the Presidue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the Presidue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing α-BoNT/A antibodies.


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