The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2022

Filed:

Sep. 01, 2020
Applicants:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

The Uab Research Foundation, Birmingham, AL (US);

Inventors:

Sergei Zolotukhin, Gainesville, FL (US);

Sanford L. Boye, Gainesville, FL (US);

Shannon E. Boye, Gainesville, FL (US);

Damien Marsic, Rockville, MD (US);

Nicholas Muzyczka, Gainesville, FL (US);

Hector Ruben Mendez-Gomez, Gainesville, FL (US);

Paul D. Gamlin, Birmingham, AL (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C12N 15/10 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C12N 15/1037 (2013.01); C12N 15/86 (2013.01); C12N 7/00 (2013.01); C12N 2320/32 (2013.01); C12N 2750/14011 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14145 (2013.01);
Abstract

Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (e.g., variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells.


Find Patent Forward Citations

Loading…