The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Sep. 15, 2020
Rk Pharma Solutions Llc, Piscataway, NJ (US);
Ravishanker Kovi, Monroe Township, NJ (US);
Jayaraman Kannappan, Vadodara, IN;
Sai Saisuryanarayana Donthukurthi, Gujarat, IN;
Shivam Saroj, Anand, IN;
Piyush Fadadu, Vadodara, IN;
Srikrishna Apar, Aurangabad, IN;
Sandeep Aher, Aurangabad, IN;
Veerabhadra Rao Bobbili, Vadodara, IN;
RK PHARMA SOLUTIONS LLC, Piscataway, NJ (US);
Abstract
Methods for preparing degarelix acetate are provided that include the steps of providing a suitable resin; deprotecting the resin with a diethylenetriamine solution; reacting sequentially the deprotected resin with different Fmoc protected amino acids; deprotecting the amino acid in each sequence with a diethylenetriamine solution in a stepwise fashion to yield a degarelix crude compound; and purifying the degarelix crude compound to yield pharmaceutically acceptable degarelix acetate. Methods of preparing degarelix acetate-mannitol premix and the resulting degarelix acetate-mannitol premix are also provided.