The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Nov. 20, 2020
Applicant:
Orion Corporation, Espoo, FI;
Inventors:
Oskari Karjalainen, Helsinki, FI;
Pekka Pietikäinen, Espoo, FI;
Assignee:
ORION CORPORATION, Espoo, FI;
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01);
Abstract
The present disclosure relates to an improved process for the preparation of a sulfonamide structured kinase inhibitor, namely N-(2',4′-difluoro-5-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)-[1,1′-biphenyl]-3-yl)cyclopropanesulfonamide (1A) and pharmaceutically acceptable salts thereof. Compound of formula (1A) is a selective inhibitor of FGFR/VEGFR kinase families and is useful in the treatment of cancer.