The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Nov. 26, 2018
Applicant:
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Inventors:
Peter Fey, Wuppertal, DE;
Philipp Rubenbauer, Bensheim, DE;
Kai Lovis, Dusseldorf, DE;
Britta Olenik, Bottrop, DE;
Julia Kusel, Bochum, DE;
Felix Spindler, Starrkirch-Wil, CH;
Assignee:
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 233/88 (2006.01); C07C 51/09 (2006.01); C07C 227/18 (2006.01); C07C 231/02 (2006.01); C07C 231/12 (2006.01);
U.S. Cl.
CPC ...
C07C 233/88 (2013.01); C07C 51/09 (2013.01); C07C 227/18 (2013.01); C07C 231/02 (2013.01); C07C 231/12 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention relates to a novel and improved process for preparing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoic acid of the formula (I), to the compound of the formula (I) in crystalline form and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular, cardiopulmonary and cardiorenal disorders.