The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Sep. 06, 2016
Applicant:
LA Jolla Institute for Allergy and Immunology, La Jolla, CO (US);
Inventors:
Nunzio Bottini, San Diego, CA (US);
Cristiano Sacchetti, San Diego, CA (US);
Stephanie M. Stanford, La Jolla, CA (US);
Assignee:
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 38/46 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01); C12Q 1/6883 (2018.01); A61K 45/06 (2006.01); G01N 33/68 (2006.01); A01K 67/027 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 38/465 (2013.01); C07K 16/40 (2013.01); C12N 15/1137 (2013.01); C12N 15/86 (2013.01); C12Y 301/03048 (2013.01); A01K 67/0276 (2013.01); A01K 2217/15 (2013.01); A01K 2267/0331 (2013.01); C07K 2317/76 (2013.01); C12N 2310/3233 (2013.01); C12N 2710/10043 (2013.01); C12N 2740/15043 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/158 (2013.01); G01N 33/6893 (2013.01); G01N 2333/916 (2013.01); G01N 2800/24 (2013.01);
Abstract
Methods of treating fibrotic diseases and disorders including Systemic sclerosis (SSc) are provided. Methods include, for example, administering to a subject an effective amount of an antagonist/inhibitor of PTP4A1 protein expression or activity to treat a fibrotic disease or disorder such as SSc, or an associated pathology such as organ or skin fibrosis.