The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Sep. 10, 2020
Applicants:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Triad National Security, Llc, Los Alamos, NM (US);
Inventors:
Dan H. Barouch, Boston, MA (US);
Bette T. Korber, Los Alamos, NM (US);
William M. Fischer, Los Alamos, NM (US);
Assignees:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Triad National Security, LLC, Los Alamos, NM (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/21 (2006.01); C07K 14/005 (2006.01); C07K 14/16 (2006.01); A61K 39/235 (2006.01); A61K 39/275 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/12 (2013.01); A61K 39/235 (2013.01); A61K 39/275 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/24043 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01); C12N 2740/16171 (2013.01); C12N 2740/16222 (2013.01); C12N 2740/16234 (2013.01); C12N 2740/16271 (2013.01); C12N 2740/16322 (2013.01); C12N 2740/16334 (2013.01); Y02A 50/30 (2018.01);
Abstract
The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.