The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Nov. 08, 2019
Georg August Universitaet Goettingen Stiftung Oeffentlichen Rechts, Universitaetsmedizin, Goettingen, DE;
The University of Texas MD Anderson Cancer Center, Houston, TX (US);
Michael Zeisberg, Goettingen, DE;
Elisabeth Zeisberg, Goettingen, DE;
Bjoern Tampe, Goettingen, DE;
Gerhard Anton Mueller, Goettingen, DE;
Xu Xingbo, Goettingen, DE;
Desiree Tampe, Goettingen, DE;
Raghu Kalluri, Houston, TX (US);
Georg-August-Universität Göttingen Stiftung Öffentichen Rechts, Universitätsmadizin, Göttingen, DE;
Board of Regents, The University of Texas System, Houston, TX (US);
Abstract
Provided is a method of preventing, treating or delaying progression of a disease involving aberrant fibroblast proliferation. The method involves using a compound that reduces the level of tyrosine phosphatase activity effected by the protein EYA1A in the parenchymal organ, a nucleic acid ligase IV inhibitor, or an antisense oligonucleotide against the p53-binding protein 1 (53BP1).