The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
May. 11, 2017
Applicant:
The Jackson Laboratory, Bar Harbor, ME (US);
Inventors:
Kyuson Yun, Houston, TX (US);
Hai-Xiao Zhai, Bedford, MA (US);
Assignee:
The Jackson Laboratory, Bar Harbor, ME (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/409 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 403/14 (2006.01); C07D 487/22 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/409 (2013.01); A61K 9/0019 (2013.01); A61P 35/00 (2018.01); C07D 403/14 (2013.01); C07D 487/22 (2013.01);
Abstract
YAP1 inhibitors and methods of treating a subject with a cancer that include administering a YAP1 inhibitor are disclosed. Also disclosed are methods for determining responsiveness to a YAP1 inhibitor in a subject, methods for diagnosing a tumor in a subject including determining the level of YAP1 expression, compositions that include YAP1 inhibitors, and methods of using those compositions.