The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2022
Filed:
Jan. 17, 2020
Applicant:
Baker Heart and Diabetes Institute, Melbourne, AU;
Inventors:
David Martin Kaye, Beaumaris, AU;
Guy Krippner, Geelong, AU;
Geetha Thanga Mariappan, Bangalore, IN;
Assignee:
Baker Heart and Diabetes Institute, Melbourne, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/28 (2006.01); A61K 31/444 (2006.01); A61K 9/48 (2006.01); A61K 45/06 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2866 (2013.01); A61K 9/2886 (2013.01); A61K 9/4808 (2013.01); A61K 9/4891 (2013.01); A61K 31/444 (2013.01); A61K 45/06 (2013.01); A61K 9/2072 (2013.01); A61K 2300/00 (2013.01);
Abstract
The present invention relates to oral controlled-release formulations of 5-(pyridinyl)-2(1H)-pyridinone compounds and their use in the treatment of a subject with heart failure, a stage, class or manifestation of heart failure, or at risk of developing or exhibiting symptoms of heart failure. The formulations of the invention release the compounds in the range of between 0.1 μg/kg body weight/minute and 20 μg/kg body weight/minute.