The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2022

Filed:

Feb. 22, 2019
Applicant:

The Florida International University Board of Trustees, Miami, FL (US);

Inventors:

Anuradha Godavarty, Miami, FL (US);

Youngjin Jung, Miami, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61B 5/02 (2006.01); A61B 5/00 (2006.01); G01J 3/28 (2006.01); G01J 3/02 (2006.01); G01J 3/10 (2006.01); A61B 5/024 (2006.01); A61B 5/06 (2006.01); G01N 21/31 (2006.01);
U.S. Cl.
CPC ...
A61B 5/02028 (2013.01); A61B 5/0059 (2013.01); A61B 5/02416 (2013.01); A61B 5/065 (2013.01); A61B 5/14551 (2013.01); A61B 5/7207 (2013.01); A61B 5/742 (2013.01); G01J 3/0264 (2013.01); G01J 3/0272 (2013.01); G01J 3/108 (2013.01); G01J 3/2823 (2013.01); A61B 2560/0431 (2013.01); G01N 2021/3155 (2013.01); G01N 2201/0221 (2013.01);
Abstract

The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed.


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