The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Feb. 12, 2013
Applicant:

Japan Science and Technology Agency, Kawaguchi, JP;

Inventors:

Kazuyuki Aihara, Tokyo, JP;

Luonan Chen, Kobe, JP;

Rui Liu, Guangzhou, CN;

Zhiping Liu, Jinan, CN;

Meiyi Li, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 33/50 (2006.01); G16B 20/20 (2019.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01); G16B 40/00 (2019.01); G16B 20/10 (2019.01);
U.S. Cl.
CPC ...
G16B 20/20 (2019.02); G16B 20/00 (2019.02); G16B 30/00 (2019.02); G16B 40/00 (2019.02); G16B 20/10 (2019.02);
Abstract

The present invention provides a device, method, and program for detection of a biomarker candidate that may be used in a diagnosis of a pre-disease state indicating a transition from a healthy state to a disease state. Biological samples are collected from a subject to be measured at different times. Statistical data is obtained by aggregating measurement data obtained in measurement on collected biological samples. Thereafter, a process of obtaining high-throughput data (s), a process of choosing differential biological molecules (s), a process of clustering (s), a process of choosing a DNB candidate (s), and a process of identifying a DNB by significance analysis (s) are carried out.


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