The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
May. 28, 2020
Zhejiang University, Hangzhou, CN;
ZHEJIANG UNIVERSITY, Hangzhou, CN;
Abstract
A method for rapid and quantitative determination of sildenafil in cocktail includes the exemplary steps of: Step 1, assigning a Raman spectrum of sildenafil; Step 2, weighing and dissolving a sildenafil standard in methanol to obtain a 1,000 mg/L sildenafil standard solution, and mixing cocktails with the sildenafil standard solution, to prepare test solutions; Step 3, mixing 100 μL each of test solutions with 500 μL of surface enhancer OTR 202 to acquire Raman spectra; and Step 4, establishing a linear regression model, with a formula of y=4035.1 x+503.26, where y is the content of sildenafil in cocktail, in mg/L, and x is intensity of Raman characteristic peaks at 1584 cm. Rapid determination of sildenafil by SERS is feasible and reliable, serving as a novel, rapid, and accurate method for quantitative determination of sildenafil in cocktail. The method meets the requirements of analysis and detection of sildenafil in other alcoholic beverages.