The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Jul. 20, 2016
Applicant:

Bioarctic Ab, Stockholm, SE;

Inventors:

Lars Lannfelt, Stockholm, SE;

Hans Basun, Stockholm, SE;

Erik Rollman Waara, Stockholm, SE;

Assignee:

BioArctic Neruoscience AB, Stockholm, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2871 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7047 (2013.01);
Abstract

A method of preventing, alleviating or treating traumatic brain injury in an individual comprises administering to the individual a therapeutically effective and physiologically acceptable amount of an agent capable of reducing the amount of one or more aggregated forms of one or more peptides in the brain. An agent capable of reducing the amount of one or more aggregated forms of one or more peptides in the brain is suitable for use in preventing, alleviating or treating traumatic brain injury. A method for predication of the risk of an individual for complications after a traumatic brain injury comprises detecting one or more aggregated forms of one or more peptides prone to aggregate as a result of a traumatic brain injury event, in the brain of the individual, wherein an increased level of such aggregates in the brain indicates an increased risk for complications.


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