The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
Aug. 21, 2017
The Regents of the University of California, Oakland, CA (US);
Daniel Takashi Kamei, Monterey Park, CA (US);
Benjamin Ming Wu, San Marino, CA (US);
David Yuan Pereira, Los Angeles, CA (US);
Chloe Michelle Wu, San Marino, CA (US);
Matthew Foosing Yee, Saratoga, CA (US);
Joshua Anthony Keefe, Sunnyvale, CA (US);
Christina Caroline Pearce, Orinda, CA (US);
Amir Adam Dailamy, Calabasas, CA (US);
Vincent K. Wong, San Gabriel, CA (US);
Nguyen Khoi Le, Sacramento, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
It was discovered that hydrogel scaffolds can be used to induce phase separation as aqueous two-phase systems (ATPSs) pass through and/or rehydrate the scaffolds, allowing for concentration of target analyte(s) (e.g., biomolecule(s)) into a particular phase of the ATPS or into a leading front. Accordingly, in various embodiments methods and devices are provided that utilize aqueous two-phase systems and hydrogel scaffolds to improve the sensitivity of assays (e.g., of point-of-care assays) without sacrificing cost or ease of use.