The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Jan. 10, 2017
Applicants:

Vilnius University, Vilnius, LT;

Eth Zurich, Zürich, CH;

Inventors:

Linas Mazutis, Vilnius, LT;

Greta Stonyte, Vilnius, LT;

Vaidotas Kiseliovas, Vilnius, LT;

Rapolas Zilionis, Vilnius, LT;

Arvydas Janulaitis, Vilnius, LT;

Robertas Galinis, Zürich, CH;

Sabine Studer, Zürich, CH;

Donald Hilvert, Zürich, CH;

Assignees:

VILNIUS UNIVERSITY, Vilnius, LT;

ETH 7LIRICH, Zürich, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); B01J 19/00 (2006.01); A61K 9/50 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); A61K 9/50 (2013.01); B01J 19/0093 (2013.01); B01L 3/502784 (2013.01); B01J 2219/0086 (2013.01); B01J 2219/00912 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0636 (2013.01);
Abstract

Disclosed is a system and method for production of DNA particles and use thereof. The DNA particles can be produced by amplification of nucleic acid molecule(s). Alternatively, DNA particles can be prepared by condensing multiple DNA molecules. The DNA condensation into a particle is mainly triggered by pyrophosphate and positively charged cations (e.g. magnesium). DNA particles can be applied for numerous biological applications but not limited to directed evolution, proteomics, drug delivery and imaging. DNA particles can be used to synthesize proteins using in vitro transcription/translation reaction.


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