The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
Oct. 31, 2018
Applicants:
Lonza Biologics Plc, Slough, GB;
Pfizer Inc., New York, NY (US);
Inventors:
James Rance, Thame, GB;
Robert Young, London, GB;
Michael J. Agostino, Andover, MA (US);
Mark Moffat, St. Louis, MO (US);
Lin Zhang, Boxford, MA (US);
Baohong Zhang, Madison, CT (US);
Assignees:
LONZA BIOLOGICS PLC, Slough, GB;
PFIZER INC., New York, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 15/90 (2006.01); C07K 16/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 16/00 (2013.01); C12N 15/10 (2013.01); C12N 15/90 (2013.01); C12P 21/00 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C12N 2800/22 (2013.01); C12N 2800/30 (2013.01);
Abstract
The present invention relates to stable and high-producing site-specific integration (SSI) host cells, e. g. Chinese hamster ovary (CHO)-derived host cells, methods to produce and to use them.