The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
Dec. 02, 2020
Exuma Biotech Corp., West Palm Beach, FL (US);
Gregory Ian Frost, West Palm Beach, FL (US);
James Joseph Onuffer, Jr., Alameda, CA (US);
Ghiabe H. Guibinga, San Diego, CA (US);
Farzad Haerizadeh, San Diego, CA (US);
Frederic Vigant, Villers-sous-Saint-Leu, FR;
Anirban Kundu, West Bay, KY;
Exuma Biotech Corp., West Palm Beach, FL (US);
Abstract
The present disclosure provides methods and compositions for genetically modifying lymphocytes, for example T cells and/or NK cells, in shorter times than previously and/or in whole blood or a component thereof. In some embodiments a lymphodepletion filter assembly is used before or after forming a reaction mixture where lymphocytes are contacted with recombinant retroviral particles in a closed system, to genetically modify the lymphocytes.