The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
Dec. 04, 2020
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Jef De Brabander, Dallas, TX (US);
Qiren Liang, Dallas, TX (US);
Beth Levine, Dallas, TX (US);
Wei-Chung Chiang, Dallas, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 231/06 (2006.01); C07D 403/04 (2006.01); C07D 231/12 (2006.01); C07D 401/04 (2006.01); C07D 413/10 (2006.01); C07D 413/04 (2006.01); C07D 409/04 (2006.01); C07D 405/06 (2006.01); C07D 417/04 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); C07D 231/06 (2013.01); C07D 231/12 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 417/04 (2013.01);
Abstract
Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.