The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Mar. 14, 2018
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Carlos Francisco NG Pitti, Jamaica Plain, MA (US);

Ulri Nicole Lee, Seattle, WA (US);

Richard Novak, Boston, MA (US);

Olivier Yves Frederic Henry, Brookline, MA (US);

Remco Van Erp, Sint Anthonis, NL;

Donald E. Ingber, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 27/08 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502707 (2013.01); B01L 3/502715 (2013.01); G01N 27/08 (2013.01); G01N 33/48707 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0896 (2013.01);
Abstract

A fluidic device includes a fluidic layer, a capture material, and an electronics layer, the fluidic layer includes a main channel and a pair of sample channels fluidly coupled to the main channel. The pair of sample channels is configured to receive and introduce a sample material into the device. The sample material includes an analyte. The capture material is positioned in a portion of the main channel that is spaced from the pair of sample channels. The capture material has a three-dimensional matrix of receptors therein configured to bond with the analyte. The capture material has a length that is associated with a dynamic range of the fluidic device and a cross-sectional area that is associated with a sensitivity of the fluidic device. The electronics layer includes electrodes configured to measure an electrical resistance through a portion of the capture material.


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